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More studies focusing on understanding how various neurotransmitters and mediators released by the ENS and extrinsic neurons modulate immune responses to CDI could provide insight into novel pharmacological approaches to balance the host response, improve the management of CDI and prevent gastrointestinal dysfunction post-infection

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By integrating the network graph and the topological attributes table, we identified five key targets associated with UC, including REN, LNPEP, HLA-A, OXTR, and SIRT1